INCLUSION OF PF68 SURFACTANT IMPROVES STABILITY OF RAAV TITER WHEN PASSED THROUGH A SURGICAL DEVICE USED IN RETINAL GENE THERAPY

Inclusion of PF68 Surfactant Improves Stability of rAAV Titer when Passed through a Surgical Device Used in Retinal Gene Therapy

Recent advances in recombinant adeno-associated virus (rAAV) gene therapy for choroideremia show gene replacement to be a promising approach.It is, however, well known that contact of vector solution with plastic materials in the surgical device may result in non-specific adsorption with resulting loss of physical titer and/or level of protein expr

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Breathe Easy EDA: A MATLAB toolbox for psychophysiology data management, cleaning, and analysis [version 2; referees: 2 approved]

Electrodermal activity (EDA) recordings are widely used in experimental psychology to measure skin conductance responses (SCRs) that reflect sympathetic nervous system arousal.However, irregular respiration patterns and deep breaths can cause EDA fluctuations that are difficult to distinguish from genuine arousal-related SCRs, presenting a methodol

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